BSeq-sc: Deconvolution of Bulk Sequencing Experiments using Single Cell Data
BSeq-sc is a bioinformatics analysis pipeline that leverages single-cell sequencing data
to estimate cell type proportion and cell type-specific gene expression differences from
RNA-seq data from bulk tissue samples.
How to cite BSeq-sc
When using this work in any way, please cite the following publication:
A single-cell transcriptomic map of the human and mouse pancreas reveals inter- and intra-cell population structure
M. Baron, A. Veres, S.L. Wolock, A. L. Faust, R. Gaujoux, A. Vetere, J. Hyoje Ryu, B. K. Wagner, S. Shen-Orr, A. M. Klein, D. A. Melton, I. Yanai
Cell Systems. 2016 Oct 26 10.1016/j.cels.2016.08.011
Installation
# install devtools if necessary
install.packages('devtools')
# install the bseqsc package
devtools::install_github('shenorrlab/bseq-sc')
# load
library(bseqsc)