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We are trying to run demuxlet with 8 individuals, using the suggested `--alpha 0 --alpha 0.5` parameters
We are getting 82% ambiguous calls, 13% doublets and 5% singlets.
As discussed in one of …
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Hi! I am applying AMULET on snATAC-seq data generated from my lab. For a dataset like this, after filtering with TSSE >= 10 and log10(UQ + 1) >= 3 (UQ means the number of uniquely mapped fragments), t…
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Hey, thank you for the great package.
I suggest an improvement on the documentation / recommendations.
### You currently write:
> If you did not provide it (dbr argument), the doublet rate wi…
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Now the experimental miri stacked borrows consider this as Undefined Behavior
```
error: Undefined Behavior: not granting access to tag because incompatible item [Unique for ] is protected by call …
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Hi,
https://signetfaucet.bublina.eu.org/ is sending really small amounts, eg 836 sats in https://mempool.space/signet/tx/9337037cad2c0f441e7802a356d9c794f962894cd89900dafb5228670d2acc48 despite hav…
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This could be very useful in a lot of contexts, especially in science texts.
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Hello vireo developers,
I have a small issue to report, please see the details below:
**Background**
We're performing pooled single nucleus RNA-seq experiments, and are planning to demultiplex …
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I like to use Github issues as TODO lists. First item of business: conflicting UMIs.
## The problem
UMIs are used by `demuxlet` and appear in the `UB` tags within the BAM file. When we create doub…
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### Please make sure these conditions are met
- [X] I have checked that this issue has not already been reported.
- [X] I have confirmed this bug exists on the latest version of scanpy.
- [ ] (option…
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I'm trying to run demuxlet with 8 individuals, and I always get a lot of doublet calls, but strangely not many AMB calls. I saw the discussions in previous issues [here](https://github.com/statgen/pop…