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This issue is about handling an "impossible" intersection by static type checkers. We consider two cases:
### It must be transformed to `Never`
Arguments in favor:
- @mikeshardmind [argues](ht…
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Hello
I am working on a clonal organism but we believe more and more it might not be so clonal. We have HiFi data and I want to use them to detect MAF. Is it possible with DeepVariant to detect tha…
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_[Edit, mit-mit, Feb 2024 This feature launched in Dart 3.3; we have [docs here](https://dart.dev/language/extension-types).]_
_[Edit, eernstg: As of July 2023, the feature has been renamed to 'ext…
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# Question
Output of `python -c "import pydantic.utils; print(pydantic.utils.version_info())"`:
```
pydantic version: 1.4
pydantic compiled: False
inst…
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(1)HiFiCNV detected significantly fewer DEL/DUP variant sites than sniffles
(2)When calculating the same mutation sites of sniffles and HiFiCNV, it was found that multiple sites of sniffles corre…
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- [ ] Proposal added
- [ ] Discussed in LDM
- [ ] Decision in LDM
- [ ] Finalized (done, rejected, inactive)
- [ ] Spec'ed
See also https://github.com/dotnet/roslyn/issues/115
## Design revi…
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hi,I ran into some problems when I ran bactopia using docker, as follows:
(bactopia) root@6f9443c7a667:/# bactopia --R1 /home/fastqs/43_HQ_R1.fq.gz --R2 /home/fastqs/43_HQ_R2.fq.gz --sample kp43 --…
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### Problem Statement
Ion contains types that are structurally identical, but differ only in their _type_. In our current factoring of `Value`, we end up creating variants that are basically the s…
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**Have you checked the FAQ? https://github.com/google/deepvariant/blob/r1.4/docs/FAQ.md**: Yes
**Describe the issue:**
(A clear and concise description of what the issue is.)
A variant with VAF…