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When the Zotero server detects multiple DOIs or other resource identifiers it will return a JSON object with the possible resources listed as 'items:'. These are intended to be selected from by the us…
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Hello! I am running into an error when running a calibration check in the low MOI. It looks like this:
```r
Running setup. ✓
Constructing negative control pairs. ✓
Generating permutation resam…
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Hi,
I am wondering if MAUDE is designed for seeing the impact of guide RNAs on ONE target gene or if it also applies for whole genome FACS screening. In the tutorial it is all about one gene.
Fo…
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Hello, and many thanks for writing CRISPOR!!
I have been able to locally install CRISPOR on an Ubuntu 18.04 OS, in order to run it from the command line. I downloaded the hg38 genome from http://cr…
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# Background
A piece of information missing from the target page is whether the target can be catalogued as a *core essential* gene. These genes are unlikely to tolerate an inhibition and are there…
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Hi,
I have cloned this software locally and want to run for a new species genome. I want to know whether the mRNA sequence not each exon sequence for an mRNA can input when provided a gff annotation …
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Let's evaluate how well we can translate profiles across experimental conditions.
We could pick several different pairs of conditions in this dataset, but we're considering focussing on cell type t…
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Thanks for your work and sharing of the dataset! It's a very useful resource. But it confuses me when I met the genetic perturbation, labelling as ORF (trt or control). It means it's not CRISPR, right…
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Thanks for maintaining this suite of packages.
I just ran into a series of problems when using `addSpacerAlignments` with `bowtie` instead of `biostrings` as aligner.
Basically I'm working with bact…
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Hi! I was pointed towards here through the ENCODE preprint ["Multi-center integrated analysis of non-coding CRISPR screens"](https://www.biorxiv.org/content/10.1101/2022.12.21.520137v1.supplementary-m…