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# nf-core/sarek feature request
## Is your feature request related to a problem? Please describe
TMB / tumor mutational burden is a key metric for many oncology related projects and thus could b…
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![RRQVJ8 H@9Y~_)P%MC ZF(9_tmb](https://github.com/user-attachments/assets/744902d8-8106-46dd-b148-523539040c36)
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- [ ] basic
- [ ] add random effects
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技术老师您好!数据所在的盘剩余内存有100多G,但在在建立索引这一步出现了以下问题,想请教您这个应该如何解决?谢谢您!
![_P2KX1T_J(GSI4_%}A4XBV4_tmb](https://github.com/user-attachments/assets/14915db0-9d41-4558-99e5-7dd25bb4a91b)
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github actionsでtestを実行するとき,tmbのコンパイルがうまくいかずにエラーになってしまう(とりあえずtmbを使うテスト部分はコメントアウトした https://github.com/ichimomo/frasyr/pull/848).
パッケージ内でtmbを使うときにはもっと正式なやり方があるようなので,それに移行したい.
たとえばこのサイトを参考に,cppファイルをhpp…
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Reprex:
```r
library("mmrm")
fit
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When working through this [demo](https://pbs-assess.github.io/sdmTMB/articles/basic-intro.html) on a new computer and a fresh install of R (4.3.2), we are running into the following issue:
```
lib…
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We are getting quite frequent warnings in our Coherence log on storage enabled nodes mentioning "initiating connection migration with tmb" and I would like some info about what it means on a more tech…
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I'm finding my file won't compile if I read in parameter vectors inside an if statement, and then write an equation using those parameters. Can TMB do this? Or is there a workaround so that you can re…