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Hi, I have two 27-mer long peptides (pvacfuse generate_protein_fasta) for ERC1_PLAGL1 gene fusion from three different gene transcript combinations. However, these long peptides have the same HLA-epit…
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Can I use ProtTrans pretraining, add a fully connected layer, and change the loss to MSE for predicting some problems such as thermal stability?
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Hi, I have run WaterSwap with Sire 2023.1.1 on protein 1OIT and each time the calculation completes an iteration the structure becomes a bit more warped.
After 429 iterations the protein was looking …
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Discussion on how to construct meta titles and descriptions:
https://docs.google.com/document/d/1R8ocUllm8EV3SPd5XBkY1rIC8sZgYVV1A93dsA7QujQ/edit#heading=h.kh7oxyc39a8c
DoD:
1. Add tissue descriptio…
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### Week 1 - Get to know the community
- [X] Join the communication channels
- [X] Open a GitHub issue (this one!)
- [x] Install the Ersilia Model Hub and test the simplest model
- [x] Write a motiva…
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Hi all,
I've been looking at speeding up my FEP calculations. While I've been looking at increased end state sampling using a variety of enhanced sampling methods, an easy win looks like using hydr…
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Should telomere capping be an activity, rather than a process?
The process is
GO:0031848 | protection from non-homologous end joining at telomere
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I don't think these are correct. The annotations are not transferred from the orthologs oif hrb1 and some are from other pombe RNA binding proteins.
I will try to dig out some evidence but I carefu…
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***New BP Term: Target-directed microRNA degradation**
*Definition: The process in which a miRNA targeted for degradation by a non-coding RNA or mRNA. The binding of a miRNA by an RNA within a RISC…
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**Submitting author:** @JosePereiraUA
**Repository:** https://github.com/sergio-santos-group/ProtoSyn.jl
**Version:**
**Editor:** @odow
**Reviewers:** @jgreener64, @mfherbst
**Managing EiC:** Va…