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Hi @FreekManders and everyone,
Is there a way to use MutationalPatterns to get the SNVs correspond to a specific mutational signature?
I assume that the absolute contribution means the number of…
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- For BINARY (e.g. mutational signatures), we can do Fisher’s exact test and render the data similar to Mutations.
![image8](https://user-images.githubusercontent.com/15748980/95222103-288a3f80-07c…
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> Analysis and visualization of experimentally elucidated mutational signatures
What kind of analyses can be done? A vignette demonstrating use with an example VCF file like in Bioconductor would b…
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- [x] Methylation tab cBioPortal/cbioportal#7683
- [ ] Should we support continuous CNA data?
- [x] Support patient level enrichments analysis cBioPortal/cbioportal#4637
- [x] treat overlapping pa…
jjgao updated
8 months ago
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Hi,
I have been exploring the package and so far it has been very useful (specially since it is my first time working with mutational signatures). I generated the freq/Count of a number of selecte…
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Hello! I find this tool incredibly useful. Just one possible enhancement could be to report the upstream and downstream bases (context) of the mutation to make it easier to make mutational signatures …
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Hello,
I am trying SUITOR to extract signatures from cancer mutational catalogs. However, the "rec" object that is created after running the suitor() function, does not have any information on the W …
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The idea is to build a classification algorithm for languages based on the frequency of occurence of a given charfacter set. These would work similar than mutational signatures.
The idea is to downlo…
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Hi there!
I've been interested in estimating the contribution of mutational signatures defined originally with whole-genome data to variant calls from panels such as MSK-IMPACT ; I wonder what the…
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Can you please curate this study?
http://www.nature.com/ng/journal/v48/n10/full/ng.3659.html