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[Meropenam.pdf](https://github.com/Open-Systems-Pharmacology/PK-Sim/files/1398398/Meropenam.pdf)
I am trying to build a PBPK model for meropenem.
70% of the drug is excreted unchanged in urine. I w…
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with PK-Sim® and MoBi® for Quantitative Systems Pharmacology
-> with PK-Sim® and MoBi® for PBPK and Quantitative Systems Pharmacology
or
-> with PK-Sim® and MoBi® for Quantitative Systems Pharmacol…
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Dear all,
as far as I know PK-sim predicts the pH-dependent solubility from a given solubility at a reference pH and the pKa values of the compounds. However sometimes you have the luxury of measur…
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I would add a link to Donato's tutorial: [this](https://github.com/Open-Systems-Pharmacology/OSP-based-publications-and-content/issues/97) or directly [this](http://onlinelibrary.wiley.com/doi/10.1002…
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heading: subheading (->link)
PBPK model building: Building a simple PBPK model of ciprofloxacin (-> ISSX Session 2)
PK Drug-Drug-Interaction: Simulating the DDI of rifampicin and midazolam (-> ISSX …
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Good day everyone,
I am validating a PBPK model built in PKSim using different data sources. I would like to compare the predicted PK Parameters, such as **Total CL** and **Vss**, with the paramete…
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generate issue in [pub-list](https://github.com/Open-Systems-Pharmacology/OSP-based-publications-and-content/issues) (i.e. publications and content repo) for each hands-on exercise and link at least o…
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In Tutorials section, add 2 hands-on exercises on the web-page, so people know that this is not only videos
(select any 2 from [the list](https://github.com/Open-Systems-Pharmacology?utf8=%E2%9C%93&q…
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Dear all,
I am simulating PK data using PBPK model. I want to obtain the PK profile different individuals and compare the output using data coming from a clinical trial. I have a few questions tha…
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Good day everyone,
We are currently validating a PBPK model built in PKSim using different historical clinical trials.
For most of these clinical trials, specific (oral) formulations are used with…