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Attached are a set of terms which have been requested when developing a disease model for this disease. I have put these into broad groups. I think that the existing term HP:0002270 'Abnormality of t…
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Hi,
Could I get a new term "enteric nervous system
development"? This would be a part of "autonomic
nervous system development". Autonomic nervous system
development would be a part of peripheral ner…
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See open ticket #893
Please add:
abnormal enteric neural crest cell morphology
DEF: any structural anomaly of the neural crest cells that arise predominantly from the vagal region of the neural tube…
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Please add the following as a children terms of "abnormal neural crest cell migration [MP:0002950]"
abnormal enteric neural crest cell migration
DEF: any anomaly in the migratory path or behavior of …
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Please add:
1. abnormal interstitial cell of Cajal
SYN: abnormal interstitial cell of Cajal morphology
DEF: any structural abnormality in the type of cell found in the gastrointestinal tract and serv…
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By definition it seems like abnormal enteric cholinergic neuron morphology (MP:0001047) ought to be a child of abnormal cholinergic neuron morphology (MP:0001038) but it isn't. I'm assuming this i…
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We may also want to subdivide neural crest cells into subtypes. We need enteric in particular.
Reported by: cindyJax
Original Ticket: [obo/mammalian-phenotype-requests/893](https://sourceforge.net/…
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Please add:
abnormal vagal neural crest cell morphology
DEF: any structural anomaly of the neural crest cells (NCCs) that arise from the vagal (neck) region of the neural tube (vagal neural crest), a…
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This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and a…
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Please consider adding "interstitial cells of Cajal ". A review describing this cell type is PMID: 16460275.
Suggested def: "A cell found in the gastrointestinal tract and serves as a pacemaker that…