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作者您好,非常令人深刻的工作,目前我在重复示例相关工作时,通过Linux系统首先通过Conda建环境,包括用conda安装GenomicRanges和IRanges,在JupyterLab下面运行示例代码:
```
system.time(
#1.start to run the wrapper functions for example.
Pagwas_data
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I wanted to estimate genetic correlation between two binary trait, The summary statistics beta and se are based logistic regression. Their Zscores range are [-8.881,7.614], and [-4.398,5.029]. When I…
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Thank you so much for your fast response to the previous issue. I am currently applying the GIFT_summary function on a real data example. The true causal gene should be gene4. The input for GIFT_summa…
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**Please make sure that this is a feature request! If you have questions about how to use TwoSampleMR please use the [Discussions](https://github.com/MRCIEU/TwoSampleMR/discussions) function instead.*…
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Hi CGWAS,
Please see the error below. I am not sure why I met the error.
"Error in summary.connection(connection) : invalid connection"
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cgwas(gwasFilePath,…
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Hello,
Thank you for developing DENTIST!
Rencently, i performed DENTIST with some gwas summary statistics , some of them stopped with an error that SNP [rs182295383] has variance of 0. Should I …
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Hello , I am using DENTIST 1.3 and using GWAS summary statistics data downloaded from PGC and UK Biobank imputed genotypes file as input.
This is what i have in my log file which seems strange to me…
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Hello
I ran the dentist with GWAS summary statistics data. It stopped with an error that a SNP with maf of 0 found. Should maf which are 0 be removed in the input file.
There was also a warning…
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Hello
I have summary statistics for GWAS bipolar disorder. I can see from the input files used for ARCHIE analysis to be correlation matrix files. Did you run correlation analysis with eQTLs summar…
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Hi there,
Thanks for the awesome resource!
I've noticed there's at least several GWAS that (I believe) should be open-source but nevertheless are missing the VCF files on OpenGWAS.
For examp…