-
Dear generatebio github,
I have gpu node that is not connected to the internet and thus need to run chroma offline.
Can you help me how to set up and call out the downloaded weight?
I appreciate yo…
-
Hello!
Thank you for publishing your work! I'm currently experimenting with your software, and I have some ideas in mind, but I am not sure to what extent they are practical and possible with RFdi…
-
I got error with paras like this, i wonder if it is a incompatible problem that i try to design binder for more than one molecule? ['contigmap.contigs=[C/0 F/0 100-120]', 'ppi.hotspot_res=[C80,C82,C86…
-
We had some questions concerning variables the modelling of variables where the property is in relation to some kind of reference point. Take [Root mean square deviation of atomic positions](https://e…
-
Hi,
I've heard of this strong model which can learn atomic coordinates. Now I want to adapt this model for my project, but I find the code is a bit complicated and hard to follow. (The paper also c…
-
I have two proposals, not sure which ones are within the scope of this:
1) Compare protein language models as well in addition to small mol SMILES?
(or if you want to keep it to small mols)
2) us…
-
We aim to cross-link with established database curators such as the Human Protein Atlas, the CL Group, HubMAP, and work towards other more niche areas such as cbio portal. We expect this will drive tr…
-
Hi,
I am testing RFDaa for the design of small molecule binders where the small molecules are covalently bound to the protein, a bit similar to the bilin reported in the paper.
I would like to k…
-
Hello,
Thank you for your work on ProteinMPNN!
I encountered a bug when I was trying to run the pipeline on a sample with several short unknown chains (like `'P' = 'XXXX'`). Those chains were no…
-
Dear Maintainers,
I have a question regarding the results on the docking tasks in the Tartarus paper. Could you help me understand how the docking scores shown in Tartarus/mols_jupyter/docking.ip…