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Hi,
does anyone know, what could be wrong when I receive this error message:
Reading annot matrix from ----/Filtered_baseline.[1-22] ...
Traceback (most recent call last):
File ".../ldsc/lds…
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Recently, I have been trying to use LD regression to estimate heritability for each allele frequency range in my data. I read the tutorial from github and understand that I need to calculate partition…
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Hi, I am trying to use your software to calculate the genetic correlation between phenotype1 and phenotype2, but the estimated heritability of phenotype1 is negative, thus I cannot get the genetic cor…
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Hi,
I've successfully replicated results using some of the ldscores from the most recent biorxiv paper for partitioned heritability (Heritability enrichment of specifically expressed genes identifi…
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Need to find a way to quantify the improvement of power via heritability. The number of significant gene could works, but variance explained seems to be a better indicator.
Maybe utmost paper have…
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Hi there,
I run CELLEX and now am running CELLECT on Hippocampus dataset of http://dropviz.org.
Genes are originally mouse gene names, I mapped them to human Ensembl IDs using Ensembl Biomart.
…
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Thanks for the tool.I want to calculate the heritability mediated by three genes on chromosome 21, but I encountered an error. What could be the cause of this problem? Following is the script.
Than…
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Prompting for non-conformable arguments when using MRAPSS::est_paras.
Are the matrices multiplied in the correct dimension and order?
here is the code and output to repeat the problem.
```{r}…
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Hi, sorry for so many question,
but I am really interested in your method.
I wanted to double check with you the intercept you refer to in the paper and make sure my interpretation is correct.
belo…
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Could you please comment: if you have low ratio values (and also low h2 for one of the phenotypes) for two continuous phenotypes (both summary statistics are GC corrected), can the genetic correlation…