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egonw updated
3 years ago
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I would like to know what publications associate targets and ligands such that the publications explicitly note some interaction/relationship between the pair (not just the target or just the ligand).…
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Here, I report the heatmap for Top similarity and top anti-similarity pairs without known evidence behind it.
Procedure:
1. Select top 20 similar pairs according to ORF profiles cosine similarity …
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when we try to test GPCR solubility method, after AFseq job running, the sequences all fold into helixes and Beta sheet bundles. Anything we handle not correct? Do we need to change the initiate GPCR…
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These 4 items exist in Wikidata but aren't connected in any way. They would be useful to be able to answer questions like: What drugs could I use to inhibit the action of ABL2?
[protein kinase inhi…
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It is taking around 4-5 hours to run on one exome VCF of around 90K variants
(running on Xeon 32 core processor + 120Gb Ram workstation)
Is it normal run time you expect?
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Thank you very much for creating a good model and sharing your data.
I would like to train the model on proteins other than the ones you used, and I was wondering if you have any contact map data fi…
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Following up to this issue on [facet search data](https://github.com/opentargets/issues/issues/3268), the FE team should now think about a UI for the new feature.
This ticket will capture all further…
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As far as @hattrill and I can tell, all dopamine receptors are GPCRs.
Please
- [ ] change label
- [ ] move under [G protein-coupled receptor signaling pathway](http://purl.obolibrary.org/obo/…
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Hi, I am trying to run DeepAffinity on the PDBind dataset, and am running into issues when trying to use the SSpro/ACCpro to get the the secondary structure and exposedness predictions for the protein…