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Thank you for providing an example to find sequence_locations such as dbSNP IDs for a given gene and allele at https://github.com/cpicpgx/cpic-data/wiki#allele (e.g. CYP2D6*3).
In practice, users w…
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**Description**
I am looking into the ADMET group in single instance prediction. For some of the datasets, a small subset of molecules appear both in the `train_val` and `test` datasets.
**To Repr…
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Dear StellarPGx,
I'm applying your pipeline for using in pharmcat and I got this error message. im running it through our cluster. Please advise how I can fix this problem.
this is the command
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As a **developer** I want **to integrate and harmonise star allele data from PharmGKB into the Platform** because **these are clinically relevant associations that our users expect to see in our widge…
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There is this very well structured code for ADME prediction: https://github.com/swansonk14/admet_ai
We should have this model in the hub. It seems be straightforward according to the README file, bu…
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I want to set an omega matrix to zero for a simulation. I don't see a way to modify the covariance with model piping (in the vignette). Is that possible?
``` r
library(nlmixr2)
#> Loading requi…
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Hi, Can I use PYPGX with a VCF created outside of it, like one generated by DRAGEN? Do I still need 'depth-of-coverage' and 'control-statistics' files? Specifically, I'm curious about using the pipeli…
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Hi there,
I've generated my own profile using:
aldy profile S000029_S4842Nr1.bam > panel.profile
But when I attempt to run this with:
aldy genotype -p panel.profile -g cyp2d6 S000029_S4842Nr1.…
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WhatsHap 2.0
Run via Docker quay.io/biocontainers/whatshap:2.0--py38h2494328_0
`whatshap polyphase --ignore-read-groups -o phased.vcf --reference=chr22.fa clair3.vcf.gz sample.bam --ploidy 2`
I r…
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I think we should modify so that .
Same case with synergy as DXM + Ketamine (both substances exert their effects mainly via NMDA antagonism).
There may be also possible serotonin syndrome, as …