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Hi,
We are currently running a partitioned heritability analysis with our annotation and 10 GWAS. Some of them don't include the frequency of the SNP, and even though I have observed that this inf…
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How to interpret the occurrence of "NA" in the "corr" column in the result file?
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Expected Behavior
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In addition to datasets, allow the user to select a specific trial for analysis.
This should also b…
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Dear all,
I am experiencing an unusual error when trying to run any kind of partitioned heritability analysis. I believe this is a bug related to the _splitp function in sumstats.py. The error occu…
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Hi there,
FYI, when attempting the example Heritability and Genetic Correlation on the wiki, the first two commands do not work:
# Download Data
wget www.med.unc.edu/pgc/files/resultfiles/pgc.c…
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1. Is assortative mating and genetic heritability considered (for behaviors)?
2. Can the liberal vs conservative divide be seen as hyperparameter optimization "learning rate"? (see [here](http://www.…
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Hi,
I am currently calculating heritability in WGS data using the GREML-LDMS method. However, I am facing an issue at the "segment-based LD score" step while running "gcta64 --bfile test --ld-score-r…
yjge updated
5 months ago
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I wonder whether it is possible to use LDSC for X chromosome analyses - specifically to evaluate polygenicity, heritability and genetic correlation between traits.
I am unable to find any examples…
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I wanted to estimate genetic correlation between two binary trait, The summary statistics beta and se are based logistic regression. Their Zscores range are [-8.881,7.614], and [-4.398,5.029]. When I…
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Hi. I'm trying to use LDSC to get heritability estimates for non-European populations. I'm running the following command:
python ~/Programs/ldsc/ldsc.py --h2 $folder.$pheno.sumstats.gz --ref-ld-c…