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I used spaln to annotated a gene structure in de-nove assembly using a homologous protein, but spaln report error (Segmentation fault (core dumped)). The command as follow
spaln -Q3 -O0 -KP -C1 -M100…
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```
We are lab-scale beasts and yet the molecular-scale nature of the things we
inhale and imbibe have lab-scale effects on us.
To describe this sort of thing we need, if only to describe samples in…
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Last week I tried the pdb 7LHY structure where I mutated A:S successfully. When I wanted to try a different mutation I received the error "invalid chain or residue position". I tried different positio…
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It would be useful to have an overview of the zettelkasten viewed as a directed graph. I was thinking d3 could be used to make this visualization.
Something like https://observablehq.com/@d3/force-…
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**- Describe the feature:**
Dear fragpipe developer team,
Thank you very much for developing this excellent tool, I would like to ask if fragpipe supports searching peptides for 3 amino acids other …
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Creating this thread to post potentially useful info about _Bacillus subtilis_ that people come across.
Quick background: _Bacillus subtilis_ is a bacterium that is widely used in industrial biotec…
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I wanted to restart the discussion about how we should best implement constant-pH methods into OpenMM, and most importantly, which layer this should be implemented into.
The best strategy is to combi…
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Hello
I'd like to run a hyper-parameter search using my own dataset, where the maximum protein length is significantly longer than the trial data (a maximum of 575 amino acids). Could you tell me w…
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### Describe the issue
When VEP adds the `LoF_info` annotation, it does not sanitize its output and allows commas in the LoF_info subfield. For example:
```
[...]|PERCENTILE:0.7,GERP_DIST:-366.3[..…
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**Description**
I generated types from https://benchling.com/api/v2/openapi.yaml file, and all of the required attributes are shown as optional in typescript.
| Name | Version …