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Dear curators,
I was wondering if you could add an option to estimate and statistically test the heritability, more or less like GEMMA does with "PVE" in Linear Mixed Models with the kinship matrix o…
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Hi,
Thank you for developing such an useful tool!
I am wondering how to obtain the estimated heritability of a disease from the return of the function ```glmmkin```. I tried the command as follows…
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Dear Dr. Gustavo
The heritability I calculated using BGLR is significantly lower than the heritability reported in the literature. And no errors were reported during the BGLR operation.
The followin…
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Hi,
I am trying to run the AnnoPred example code (when heritability estimation not provided) but got the following error. May I ask what the problem is and how can I fix it?
```
(ldsc) $ bash o…
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Prompting for non-conformable arguments when using MRAPSS::est_paras.
Are the matrices multiplied in the correct dimension and order?
here is the code and output to repeat the problem.
```{r}…
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Hi @zhenin ,
Thanks again for making this software available. I was wondering if it'd be possible to add an option to the package for chromosome-specific heritability and rg estimation? This will m…
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Hi,Zhou!
I read your article on the tomato pan-genome, fantastic job! But I get confused when I read your method section about genome-wide association study, you said that "After pruning using…
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Hello,
Does LDSC analyze structural variants, such as deletion, inversion?
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Hi Mingxuan,
Thanks a lot for your great work of XPASS and detailed examples.
I applied your software on our data with unknown population ancestry information, therefore, I chose the sd_method…
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Dear Mike,
I am wondering How LD clumping was performed to select eQTLs for candidate gene in eQTL-based two-sample Mendelian Randomization? How to handle pleiotropy eQTL issue? for example, a SNP …