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Hello,
it looks like location of datadir is set (in `network_loader.py`) as:
`datadir = '/gscratch/spe/mpun/protein_holography/data'`
whereas it should be adjusted to wherever the code is instal…
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Hello,
I noticed that the file 'sera_343C_mediumACE2_mut_effect.csv' in your repository contains the same columns as 'sera_343C_mediumACE2_mut_icXX.csv', such as 'Lib2-230815-sera-343C_mediumACE2'. H…
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https://doi.org/10.1101/103374
> Translation initiation is a key step in the regulation of gene expression. In addition to the annotated translation initiation sites (TISs), the translation process…
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https://doi.org/10.1038/s41591-018-0177-5
> Visual inspection of histopathology slides is one of the main methods used by pathologists to assess the stage, type and subtype of lung tumors. Adenocar…
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Hi, I have a corpus of about 500,000 protein sequences and would like to apply them to existing models like ESM2 or this one for predicting the fitness effect of changing an amino-acid for another.
H…
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Originally discussed here:
- https://github.com/neurogenomics/MultiEWCE/issues/16#issuecomment-1799340362
We should asses the relationship between HPO genes and probability of Loss Intolerance …
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Hi Authors,
Is there a function that takes the WT sequence and multiple mutations as input and calculates the score for the combined mutational effect?
Thank you,
Yang
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Hi everyone!
first of all, thank you so much for the amazing work! Excited to use this model for my own research.
I was wondering how correctly interpret the output for the mutational effect pr…
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Hello,
Executed code:
shapemapper --name example --target ../FASTA/RNA.fasta --out RNA_shapemap --amplicon --modified --R1 100mM_1M7_RNA_R1.fastq --R2 100mM_1M7_RNA_R2.fastq --untreated --R1 DM…