Open-Systems-Pharmacology Forum issues

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simulations run failed:some variables became negative

#538 xixi-1995 closed 3 years ago
1
How to output a reference range of [parent drug+metabolite]?

#537 regulus92 closed 4 years ago
0
Pk-sim : the database of metabolizing enzyme is not available?

#536 Tom-eng-ux closed 4 years ago
2
Metabolism and bile clearance

#535 leeking-55 closed 4 years ago
4
Lipophilicity in PKsim

#534 AnisPBPK closed 4 years ago
2
Preterm Infant simulation not working

#533 mmalsmadi closed 3 years ago
9
MoBi does not allow committing changes in organ protein expression

#532 yishuanwu closed 4 years ago
7
How to make an intraperitoneal administration

#531 HenrikCordes closed 4 years ago
6
Simulations with pregnancy population - extrapolation dose Rat from Human pregnant

#530 AParisotto closed 3 years ago
1
Isn't there a bladder compartment in the default PK-Sim

#529 jzq90 closed 4 years ago
7
Any tutorial for setting up population?

#528 humblewarrior closed 4 years ago
1
Tissue concentration when a binding partner is present

#527 teutonicod closed 4 years ago
6
How to add a time dependency to B/P partition coefficient

#526 teutonicod closed 4 years ago
6
tissue concentration

#525 leeking-55 closed 4 years ago
3
help: why i can't show building block explorer in mobi?

#524 GUTATA closed 4 years ago
11
Simulations with pregnancy population

#523 mmalsmadi closed 4 years ago
2
Lymph Flow in the Mucosa

#522 prvmalik closed 4 years ago
8
Software change request - creating virtual individuals and populations with obesity

#521 jgg1822 closed 3 years ago
1
Sensitivity analysis

#520 AnisPBPK closed 4 years ago
4
Tissue concentration could not be further increased by increase in uptake transporter

#519 yishuanwu closed 4 years ago
10
New to Pk Sim: Tutorials are out of date

#518 Felixhad closed 4 years ago
3
How to add a reversible reaction in PKsim?

#517 shapoo1 closed 4 years ago
6
What is plasma albumin concentration in animals and human?

#516 jzq90 closed 4 years ago
4
Parameter Identification

#515 Wenjing1018 closed 4 years ago
10
allow aging - how does it work?

#514 a2mahara closed 4 years ago
8
Kp scalar value

#513 humblewarrior closed 4 years ago
9
How to add different genotypes

#512 shapoo1 closed 4 years ago
4
Using Mobi 8.0

#511 Chisenamd closed 4 years ago
0
Why hepatic clearance could surpass hepatic flow rate in PK-Sim?

#510 jzq90 closed 3 years ago
21
ISEF optimization

#509 ckcho0625 closed 4 years ago
2
Fracture Healing

#508 Chisenamd closed 3 years ago
1
PBPK/PD model of nicotine and cotinine

#507 LkKov closed 3 years ago
1
Oral Absorption

#506 jmgallo closed 3 years ago
2
What parameters should I change to have this individual / population with kidney disease?

#504 AParisotto closed 4 years ago
1
What parameters should I change to have this individual / population with liver disease?

#503 AParisotto closed 3 years ago
0
Gene Expression DB?

#505 carlosverjan closed 4 years ago
1
Geometric mean, standard deviation

#502 ckcho0625 closed 4 years ago
1
PBPK-PD model when dose is not known

#501 humblewarrior closed 4 years ago
3
How to solve these problems?

#500 Wenjing1018 closed 4 years ago
4
What's the meaning of FIRST_NEIGHBOR and SECOND_NEIGHBOR?

#499 jzq90 closed 4 years ago
5
PKsim with R/Rstudio

#498 gsharma14 closed 4 years ago
2
How to determine the transit rate for each intestinal segment from intestinal transit time?

#497 wangwei1619 closed 3 years ago
6
Is there absorption in the stomach?

#496 jzq90 closed 4 years ago
3
Is it possible to build a model from IV and PO C-T curve?

#495 jzq90 closed 4 years ago
6
What's the meaning and function of “Tablet time delay factor“？

#494 jzq90 closed 4 years ago
5
Where is the formula of food effect come from?

#493 jzq90 closed 3 years ago
0
Blood/plasma concentration ratio has no impact on PK in PK-Sim standard model

#492 teutonicod closed 3 years ago
8
Bug report: the unit problem in formula

#491 jzq90 closed 4 years ago
6
How to change formulation in Mobi

#490 jzq90 closed 4 years ago
2
Concentration in Stomach

#489 JoseDavidGomez closed 4 years ago
7

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