Open-Systems-Pharmacology Forum issues

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how to modify ordinate value in population simulation?

#589 Wenjing1018 closed 3 years ago
9
Problems with simulations in pregnancy

#588 mmalsmadi closed 3 years ago
6
Creating 'Observers' in MoBi

#587 arketkar closed 3 years ago
0
Getting drug amount for a compartment

#586 DonkeySaddle closed 4 years ago
1
How to convert transporters parameters from literature?

#585 Wenjing1018 closed 3 years ago
6
How to include 'user defined variability' in population PK modeling for 'kcat', which is 'obtained by PI'?

#584 arketkar closed 4 years ago
2
how to extend the simulation curve?

#582 Wenjing1018 closed 4 years ago
3
Where to find organs weights and tissue weights?

#581 Wenjing1018 closed 3 years ago
4
Intranasal Model to brain Using MoBi

#1664 Mahmood1212 closed 1 year ago
0
Reference/documentation for SITT and LITT

#580 moPellowe closed 3 years ago
7
Fitting ontogeny including variability using PK-Sim Ontogeny Database approach

#579 choitingy closed 3 years ago
12
PBPK model for endogenous compound need help to troubleshoot

#578 rhishi24niper closed 3 years ago
13
what is wrong with the variables became negative?

#577 Wenjing1018 closed 3 years ago
3
How to open the gene database?

#575 Wenjing1018 closed 4 years ago
3
Problem in simulation with Particle Size Distribution formulation

#576 LoaneD closed 4 years ago
4
how to interpret the IVIVE for the midazolam model??

#574 AyaSaleh90 closed 3 years ago
1
save simulation chart with the observed data

#573 AyaSaleh90 closed 4 years ago
6
Km Units

#572 Wenjing1018 closed 4 years ago
4
All building blocks and simulations gone

#571 NinaHanke closed 4 years ago
3
How to create an observer for sum of 'Total fraction of dose'

#570 arketkar closed 3 years ago
4
Plasma protein scaling factor(PPSF)

#569 nasirkalam closed 3 years ago
2
scaling down mucosa endothelial permeability in case if non-instantaneous plasma-interstitium mixing?

#568 LetiziaCarrara closed 3 years ago
0
Is there a pdf manual for PKSim?

#567 humblewarrior closed 4 years ago
1
unexpected food effect observed 24h after meal

#566 LetiziaCarrara closed 3 years ago
10
Modeling saturating partitioning into BloodCells

#565 StephanSchaller closed 3 years ago
2
How to simulate plasma concentration following oral administration without IV data

#564 chengzhzh closed 3 years ago
1
Calculation surface areas not comprehensible

#563 davbus closed 3 years ago
6
Capillary endothelium as a barrier for highly bound compounds

#562 CSchraepel closed 4 years ago
2
partition coefficients (PC)

#561 jmgallo closed 4 years ago
6
Nasal administration in MoBi

#560 Nathalie06 closed 3 years ago
1
PBPK Modeling Clearance Calculation

#559 DahmSeb closed 3 years ago
0
Antibody competitive binding to FcRn

#558 teutonicod closed 4 years ago
3
Data of few individuals missing in PK-Analysis after DDI population simulation (PK-Sim 8)

#557 arketkar closed 4 years ago
2
PBPK Modeling of Buprenorphine in Adults, Children and Preterm Neonates

#556 LkKov closed 3 years ago
1
A strange PK profile of an oral formulation

#554 wangwei1619 closed 4 years ago
5
warning message for absorption

#553 AnisPBPK closed 4 years ago
4
A PB-QSP Model of the incretin hormones GLP-1 and GIP and a DPP4-inhibitor sitagliptin

#552 PavelBal closed 3 years ago
0
Rat Database Required

#551 thPrabhath closed 4 years ago
1
Exporting to Mobi and PK-Sim Formulation Questions

#550 bobisgreat closed 4 years ago
3
Miscible solvents

#549 shapoo1 closed 3 years ago
1
Population simulation for DDI modeling: No time profile and PK analysis displayed

#548 arketkar closed 4 years ago
1
Stomach pH on Fed state

#545 fredsevmartins closed 3 years ago
1
PK-Sim Default Kdeg parameters for mechanism based inhibition

#546 georgeuf closed 4 years ago
7
Metformin and Cimetidine PBPK models

#544 NinaHanke closed 3 years ago
1
Not able to customize Gastric Emptying Time in Population

#547 arketkar closed 4 years ago
4
Reference for enzyme turnover (T/2)

#543 teutonicod closed 3 years ago
3
Distribution parameters are different using individuals or population

#542 Nathalie06 closed 4 years ago
5
How to fill in the parameter values for gastrointestinal permeability

#541 Wenjing1018 closed 4 years ago
9
Virtual Population BE

#540 divyenshah closed 4 years ago
3
Origin of volume values in registered mice

#539 aniskrache closed 3 years ago
0

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