issues
search
Open-Systems-Pharmacology
/
OSP-based-publications-and-content
Publications of all kind based on the Open Systems Pharmacology Suite
15
stars
2
forks
source link
issues
Newest
Newest
Most commented
Recently updated
Oldest
Least commented
Least recently updated
A generic avian physiologically-based kinetic (PBK) model and its application in three bird species
#415
JanSchlender
opened
2 years ago
0
Prediction for optimal dosage of pazopanib under various clinical situations using physiologically based pharmacokinetic modeling
#414
JanSchlender
opened
2 years ago
0
Application of physiologically-based pharmacokinetic model approach to predict pharmacokinetics and drug-drug interaction of rivaroxaban: A case study of rivaroxaban and carbamazepine
#413
JanSchlender
opened
2 years ago
0
The investigation of the complex population-drug-drug interaction between ritonavir-boosted lopinavir and chloroquine or ivermectin using physiologically-based pharmacokinetic modeling
#412
AndreDlm
opened
2 years ago
0
Predictive performance and verification of physiologically based pharmacokinetic model of propylthiouracil
#411
AndreDlm
opened
2 years ago
0
Patient-specific in vitro drug release testing coupled with in silico PBPK modeling to forecast the in vivo performance of oral extended-release levodopa formulations in Parkinson's disease patients
#410
AndreDlm
opened
2 years ago
0
The Use of Pregnancy Physiologically Based Pharmacokinetic Modeling for Renally Cleared Drugs
#409
AndreDlm
opened
2 years ago
0
A multi-model approach to predict efficacious clinical dose for an anti-TGF-β antibody (GC2008) in the treatment of Osteogenesis Imperfecta (OI)
#408
JanSchlender
opened
2 years ago
0
Physiologically based pharmacokinetic (PBPK) modeling of lornoxicam: Exploration of doses for CYP2C9 genotypes and patients with cirrhosis
#407
JanSchlender
opened
2 years ago
0
Physiologically based pharmacokinetic (PBPK) modeling of flurbiprofen in different CYP2C9 genotypes
#406
AndreDlm
opened
2 years ago
0
Physiologically Based Pharmacokinetic Modeling to Describe the CYP2D6 Activity Score-Dependent Metabolism of Paroxetine, Atomoxetine and Risperidone
#405
AndreDlm
opened
2 years ago
0
Development and Evaluation of a Physiologically Based Pharmacokinetic Model for Predicting Haloperidol Exposure in Healthy and Disease Populations
#404
AndreDlm
opened
2 years ago
0
Daptomycin Physiology-Based Pharmacokinetic Modeling to Predict Drug Exposure and Pharmacodynamics in Skin and Bone Tissues
#403
Yuri05
opened
2 years ago
0
Investigation of the Impact of CYP3A5 and CYP2C19 Polymorphisms on Drug-Drug Interactions between Tacrolimus and Voriconazole Based on Physiologically-Based Pharmacokinetic Modeling
#402
JanSchlender
opened
2 years ago
0
Prediction of Tissue Exposures of Meropenem, Colistin, and Sulbactam in Pediatrics Using Physiologically Based Pharmacokinetic Modeling
#401
Yuri05
opened
2 years ago
0
Prediction of pharmacokinetics and pharmacodynamics of trelagliptin and omarigliptin in healthy humans and in patients with renal impairment using physiologically based pharmacokinetic combined DPP-4 occupancy modeling
#400
AndreDlm
opened
2 years ago
0
Could Fluvoxamine Dose De-escalation Increase Treatment Compliance Without Sacrificing Efficacy in COVID-19 Patients?
#399
Yuri05
opened
2 years ago
0
Development of Physiology Based Pharmacokinetic Model to Predict the Drug Interactions of Voriconazole and Venetoclax
#398
JanSchlender
opened
2 years ago
0
Physiologically based pharmacokinetic combined JAK2 occupancy modelling to simulate PK and PD of baricitinib with kidney transporter inhibitors and in patients with hepatic/renal impairment
#397
JanSchlender
opened
2 years ago
0
Development of a Translational Exposure-Bracketing Approach to Streamline the Development of Hormonal Contraceptive Drug Products
#396
JanSchlender
opened
2 years ago
0
Model-informed bridging of rivaroxaban doses for thromboprophylaxis in pediatric patients aged 9 years and older with congenital heart disease
#395
JanSchlender
opened
2 years ago
0
In vitro CYP450 enzyme down-regulation by GLP-1/glucagon co-agonist does not translate to observed drug-drug interactions in the clinic
#394
JanSchlender
opened
2 years ago
0
Physiologically based pharmacokinetic combined BTK occupancy modeling for optimal dosing regimen prediction of acalabrutinib in patients alone, with different CYP3A4 variants, co-administered with CYP3A4 modulators and with hepatic impairment
#393
JanSchlender
opened
2 years ago
0
Poster at PAGE 2022: Dose selection by covariate assessment on the optimal dose for efficacy – application of machine learning in the context of PKPD
#392
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: Physiologically based pharmacokinetic model to predict chemotherapy exposure in infants through breastfeeding: paclitaxel as an example
#391
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: A PB-QSP platform model for T cell-dependent bispecific antibodies
#390
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: Development of a physiologically based pharmacokinetic model of Ciprofloxacin in ovine septic shock
#389
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: Dose Adaptations for Drug-Gene and Drug-Drug Interactions involving Clopidogrel – A Physiologically based Pharmacokinetic (PBPK) Modeling Approach
#388
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: Physiologically-based pharmacokinetic modeling of drug-drug interactions with ketoconazole and its metabolite deacetyl-ketoconazole
#387
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: Selection of isatuximab dosing regimen in pediatric patients with leukemia using population PK and PBPK modeling approaches
#386
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: Elucidating the complex pharmacokinetics of voriconazole leveraging a middle-out approach
#385
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: Development of a physiological-based pharmacokinetic model for tegoprazan: its application to prediction of drug-drug interactions with clarithromycin
#384
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: Physiologically-Based Pharmacokinetic (PBPK) Modelling to Predict Human Milk Exposure to Sildenafil and Bosentan: a contribution from the ConcePTION Project
#383
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: Peeling the grapefruit – investigating the drug interaction potential of grapefruit juice as CYP3A4 inhibitor using physiologically-based pharmacokinetic modeling
#382
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: PBPK model-guided assessment of a liver function test
#381
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: Species-specific Expression Databases for Physiologically Based Pharmacokinetic Modeling
#380
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: Physiologically based pharmacokinetic (PBPK) modelling of cabotegravir (CAB) to support design of microarray patches (MAPs) for the treatment of HIV positive children
#379
Yuri05
opened
2 years ago
0
Poster at PAGE 2022: A platform for mechanistic modelling of subcutaneous administration with the effect of immunogenicity within the Open Systems Pharmacology framework
#378
Yuri05
opened
2 years ago
0
Physiologically based pharmacokinetic modeling of brivaracetam and its interactions with rifampin based on CYP2C19 phenotypes
#377
JanSchlender
opened
2 years ago
0
Current and future physiologically based pharmacokinetic (PBPK) modeling approaches to optimize pharmacotherapy in preterm neonates
#376
JanSchlender
opened
2 years ago
0
A Physiologically Based Pharmacokinetic and Pharmacodynamic Model of the CYP3A4 Substrate Felodipine for Drug–Drug Interaction Modeling
#375
AndreDlm
opened
2 years ago
0
Infrastructure for quality control of handling of reference data in PBPK projects using PK-Sim
#374
AndreDlm
opened
2 years ago
0
Physiologically-based pharmacokinetic modeling of immunoglobulin and antibody coadministration in patients with primary human immunodeficiency
#373
AndreDlm
opened
2 years ago
0
Application of Physiologically Based Pharmacokinetic Modeling of Lamotrigine Using PK-Sim in Predicting the Impact of Drug Interactions and Dosage Adjustment
#372
AndreDlm
opened
2 years ago
0
Physiologically based pharmacokinetic modelling to predict the pharmacokinetics of metoprolol in different CYP2D6 genotypes
#371
JanSchlender
opened
2 years ago
0
Does the Choice of Applied Physiologically‐Based Pharmacokinetics Platform Matter? A Case Study on Simvastatin Disposition and Drug‐Drug Interaction
#369
AndreDlm
opened
2 years ago
0
Physiologically based pharmacokinetic (PBPK) modeling of piroxicam with regard to CYP2C9 genetic polymorphism
#368
JanSchlender
opened
2 years ago
1
Leveraging physiologically based pharmacokinetic modeling to optimize dosing for lopinavir/ritonavir with rifampin in pediatric patients
#367
JanSchlender
opened
2 years ago
0
Physiologically Based Pharmacokinetic (PBPK) Modelling to Predict Breast Milk Exposure of Valproic Acid
#366
JanSchlender
opened
2 years ago
0
Physiologically-based pharmacokinetic modeling to predict methylphenidate exposure affected by interplay among carboxylesterase 1 pharmacogenetics, drug-drug interactions, and sex
#365
JanSchlender
opened
2 years ago
0
Previous
Next