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Hi, I'm new to the world of drug synergy experiments and I'm using synergyfinder on R to compute 3-drug synergy scores for a research project. I'm having some trouble trying to determine if a combinat…
Lux91 updated
8 months ago
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Things seemed like they were going pretty well until this part. It puzzled me. Have you met this problem?
'''
%%time
X = ReaderWriter.read_or_dump_data(file_name=norm_join_paths(targetdata_dir_raw,…
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There are substantial differences between SynergyFinderPlus ([www.synergyfinder.org](http://www.synergyfinder.org/)) and SynergyFinder2 (https://synergyfinder.fimm.fi/). For assessing the degree of sy…
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There is indeed a **typo in the SynergyFinder 2.0 manuscript** "-" sign should be "+" at the end of multi-drug combination Bliss synergy formula, but **in the code it is correct**. We will put the no…
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Hi,
I am recently using the synergyfinder package to calculate Loewe synergy scores for a set of data. I have been facing this issue recently and hope you can assist me.
I have noticed that when us…
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I also have one suggestion for future updates of this library perhaps. The current dataloaders, if I'm not mistaken, are not considering the different dataset split strategies. Recent works have hig…
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I'm working on comparing deep learning models that predict synergy of drug pairs for cancer treatment. Some of these published models use ToxAlert to obtain toxicophore info as input data for their mo…
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**TCDC ~~CARA~~ Curated Query Service Overview**
This issue is intended to initiate implementation work on the Translator Clinical Data Committee (TCDC) ~~Curated ARA (CARA)~~ Curated Query Service…
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**Describe the problem**
To enable cancer research, I would like to suggest including functionalities to work with cancer cell line information in TDC. In DepMap, there are updates in newer DepMap re…
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In ChEMBL, the connection of a drug compound to it's target is available via the drug_mechanism field. Currently, the use-case identifying targets for known drugs is not possible with the system. Eith…