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Hi
I am trying to generate polygenic scores using PRSice v2 **without phenotype data for the target population**. i.e. I just want to use the GWAS summary statistics (and specifically the effect si…
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From https://opain.github.io/GenoPred/pipeline_technical.html#Workflow my understanding is that sumstat_prep step is done independnetly from format_target step, thus internal score files (produced by …
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We've got two nice use cases of population and statistical genetics; a third use case that could attract users and contributors could be polygenic risk score computations.
I'm only glancingly famil…
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Could ingest PRS, and maybe HLA freq data
https://www.preprints.org/manuscript/202003.0356/v1
@pnrobinson - interested in your thoughts
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This is not strictly in the domain of Mondo but Mondo is where most people see this - e.g. when browsing for genes associated with breast cancer on the monarch site
OMIM has an entry
https://omi…
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Dear Florian
Firstly, I'd like to thank you for developing a robust PRS method, SCT.
I am reproducing the result of 'Making the Most of Clumping and Thresholding for Polygenic Scores'. However, …
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Right now OakVar does not support outputting polygenic risk scores results. At the same time we are working on it and also there are many public catalogs like https://www.pgscatalog.org/ with many PRS…
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Hi @privefl , @tshmak
I am benchmarking PRS/PGS methods practiced in the [PRS tutorial](https://choishingwan.github.io/PRS-Tutorial/). Regard to Lassosum, I got some confusions. I'd appreciate if…
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As our work on this package progress, this issue can help us enumerate possible future features of the package depending on the time and interests of contributors. Some features will be needed for th…
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Hi Daniel,
My name is Nilesh Dharajiya, MD, and I am a molecular pathologist by training. I came across het.io recently and am very impressed by it. I have been playing with Neo4j since last 3 yea…