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Hi all,
I am trying to fragment a collection of compounds from [Broad Repurposing Library](https://s3.amazonaws.com/data.clue.io/repurposing/downloads/repurposing_drugs_20180907.txt), a famous repurp…
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https://www.broadinstitute.org/blog/combing-through-old-drugs-find-new-ones-covid-19
The Broad Institute’s Drug Repurposing Hub has opened its repository of nearly 7,000 drug compounds to help scien…
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This became a desiderata for some SME groups at the May Hackathon. Sometimes a knowledge sources will short-circuit your analysis. For example, you are interest in finding drug repurposing, you want d…
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Hi,
Thanks for all the work on this tool. I am having trouble getting results for DrugScore function. I tried a few other tissue types including breast, kidney, lymphatic tissue and they seemed als…
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Hi Dear Author,
Your repurposing KG looks great and comprehensive. I'm curious about the use of this KG, especially on repurposing tasks. If my understanding is correct, the "Compound" entities ref…
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http://doi.org/10.1021/acs.jproteome.6b00618 (http://pubs.acs.org/doi/abs/10.1021/acs.jproteome.6b00618)
> Identifying interactions between known drugs and targets is a major challenge in drug repo…
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## Type: Other Comment
## URL: http://transltr-bma-ui-dev.ncats.io/results?l=Type%202%20Diabetes%20Mellitus&i=MONDO:0005148&t=0&q=ef653aa8-7263-48df-b0ac-5a0b9a1344e8
## ARS PK: 1cc96129-e0b5-4287-b…
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In a recent meeting with Tony Hickey, external SME, he provided feedback on the Translator UI related to what he refers to as "convergent phenotyping", which is essentially the idea of leveraging shar…
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We will use the Repurposing Hub dashboard to select specific compounds to validate in the lab.
We will select two kinds of compounds:
1. Compounds that are predicted to have well characterized e…
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Hi Daniel,
My question concerns the benchmarking data sets in Fig. 3 of the paper "Systematic integration of biomedical knowledge prioritizes drugs for repurposing". Are those available for download?…