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There seems to be another MB.1.1.1 branch, other than MV.1, growing. It is defined by S:A67V that has been moderately beneficial on JN.1 backbone.
MB.1.1.1 > S:A67V (C21762T)
Query: C936T,C21762T,…
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This convergent mutation appears in KP.3.1.1, too.
MC.10+G22865T,G28423A(Orf9b:R47H,S:A435S)
GISAID query: G22865T, G28423A, C16332T
No. of seqs: 11(USA 1 Canada 2 UK 3 France 1 Germany 1 Denma…
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Transferred from https://github.com/sars-cov-2-variants/lineage-proposals/issues/1699
There is a little KP.2 sublineage from China that instead evolving toward a negative charged N Glycan at S:30 …
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From branch 4 of https://github.com/sars-cov-2-variants/lineage-proposals/issues/1768
KP.2+C5673T(Orf1a:P1803L)+C14220T+C3619T, C18657T,G23236T, C26936T, del21656_21658(S:K558N, F32del)
GISAID q…
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From Slack:
> I was worried that the new ARG construction procedure was creating larger polytomies than before (which could explain why we are tracing recombinants back to MRCAs at only 2 timepoint…
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LZ.2.1 [C29642T(Orf10:Q29*)]+T2746C, T3055A, T3142C, T22585C, T25496C, G362A, A22995C( Orf1a:D33N,D930E, S:K478T(rev), Orf3a:I35T)
GISAID query: C29642T,T25496C, G362A,-22995(edited)
No. of seqs: …
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KP.4.2+A15171G+T21740C, A29700G(S:S60P)+A17637G,T22197C(Orf1b:P2313S,S:I212T)
This branch suddenly emerges in multiple countries, deserve watching.
Note that the S:I212T is read as S:N211T+S:L21…
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Just noticed a small hypermutated sublineage of KP.1.1.3, hard to think it will go anywhere but worth monitoring if it grows.
KP.1.1.3 >> S:R190S (G22132T) >> S:G75S (G21785A), Orf3a:S74F (C25613T…
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KP.1.1.5+C8619T(Orf1a:A2785V)+T18547C,C13335T(Orf1a:A4357V)+C23601A(S:S680Y)
GISAID query: T18547C,C13335T,C23601A
No. of seqs: 9(USA 4(2 from Qatar), Mexico 2 Canada 3)
First: EPI_ISL_19259343…
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There seems to be an LF.1.1.1 branch that loses Orf1a mutations due to recombinant.
JN.1--LF.1.1.1
Breakpoint between 6574 and 16550
It is basically LF.1.1.1 losing G4067A and C6573T. It keep…