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Hi,
I'm running into the following error when attempting to run LDSC to get cell type-specific heritability estimates for 3 cell types:
```
*****************************************************…
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Hi,
Is there an option in GCTA to run a weighted GWAS? If not, would it be possible to implement this feature in a future update? I believe it would be a valuable addition to the program.
I atte…
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Hi,
Global rg between A and B from ldsc was -0.08 (insignificant,P=0.2). But this pair had 20 significant correlated regions, and in all of these regions, some SNPs of trait A had P < 5e-8, but all S…
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Dear developers,
as reported by another user, I am experiencing a strange output when running the example:
`./SCORE -g ../example/200_100 -p ../example/200_100.pheno.plink3 -o ../example/test -n…
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# Association
- [ ] [A simple, consistent estimator of heritability for genome-wide association studies]( https://www.biorxiv.org/content/biorxiv/early/2017/10/17/204446.full.pdf)
- [x] [Multivari…
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Hello,
Does LDSC analyze structural variants, such as deletion, inversion?
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ToDo: Investigate if the stats for this population can be custom
I see files that indicate we are using sth like a reference population for performing the ldsc analysis. Can this be customised base…
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Hi Mingxuan,
Thanks a lot for your great work of XPASS and detailed examples.
I applied your software on our data with unknown population ancestry information, therefore, I chose the sd_method…
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Hi LDSC team,
I was using make_annot.py to create thin annotation files from sample files, for a partitioned heritability analysis. I kept running into an issue where the script was creating annota…
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Hi,
I'd like to hear your opinion in terms of this concern.
One of my colleagues brought the following up.
"GCTA-COJO computes an estimate of the phenotypic variance by looking at the distribution…