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https://doi.org/10.1101/099879
> Massively parallel reporter assays (MPRAs) are a method to probe the effects of short sequences on transcriptional regulation activity. In a MPRA, short sequences a…
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Hi dear developers,
We have generated an in-silico HRMS/MS database focused on our model organism. These compounds are structurally described in the literature but are absent in the spectra databa…
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Just for interest I asked ChatGPT to "write 200 words about mycetoma and why we need new medicines for this disease"
It replied:
"Mycetoma, also known as "Madura foot," is a chronic, debilitatin…
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Dear Vadim,
I hope you are well. I have used your software successfully many times for SWATH data. This is my first time using it for diaPASEF data. I initially loaded it up with variable mods in th…
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This project is really great! I wish I better understood JavaScript, but I
don't have time to learn it.
What I am wondering is whether or not you could (and would) be able to
easily add sorting …
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Hi,
Is possible to create one spectral library from more than one organisms? My samples consists from 2 different organisms (plant-fungi), so I want to create one spectral library and then to make my…
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Hello Vadim,
you have built a great piece of software, which is of tremendous help, thank you and congrats to that! I was just wondering about how DIA-NN is predicting spectra for the library-free mo…
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Hi,
I am a phd student and i'm currently working on developing a software for crispr/cas in-silico off-target prediction.
I am testing some software before the start and i'm trying also short aligne…
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- the sequence of Camelus_dromedarius_POU_class_5_homeobox_1_POU5F1_Oct4 is located here: [oct4 sequence](https://github.com/kacst-bioinfo-lab/labwork/blob/master/data/mariam/Camelus_dromedarius_POU_c…
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Dear Vadim,
I am trying to make DIANN recognise a possible chemical modification I introduced at the cysteine level.
What I did was to call a new modification, named 3333, e.g. '--mod UniMod:3333…