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I have used dorado v0.7.1 and dorado v.5.3 base called same RNA004 dataset for m6A modification. I understand the m6A models are different. After I run modkit sample-probs --hist on the two modBa…
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The DRACH motif 6mA model is amazing!!! Are there going to be models coming out for pseudo-U and inosine?
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Hello! @marcus1487
I have run Tombo successfully with my dataset earlier. However, I used the same data and run the same pipeline again (I might add some options in resquiggle like **corrected-gro…
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Hi,
Thanks for the great toolkit.
I am interested in calling m6A and pseudoU on direct RNA-sequencing data.
I used Dorado v0.7.0 as follows:
```
dorado basecaller \
-v hac,pseU \
--min…
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First of all I would like to thank the authors for their noble work in the field of RNA modifications.
I am trying to understand the results obtained from 'inference' for the default model.
…
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### Aims/objectives.
We currently have BID-seq, eTAM-seq, and GLORI, amounting to a total of 65 dataset. We need to add more data from the public domain, esp. if we aim for a publication. We cannot…
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Hello,
I believe that m6ABasecaller is a valuable tool for m6A detection at the single molecule level, which is highly essential for our work. I have a couple of questions regarding this tool. Firs…
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Dear all,
I am kind of new to analyzing epigenetics data so you have to excuse my naive question:
When I use Dorado for basecalling m6A-RNA modifications from direct RNA-sequencing and the resulti…
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Hello,
I am using m6ANet to detect m6A modifications in RNA and recently swapped over to the new nanopore RNA004 chemistry/kit. Because of this, my pipeline uses ONT's new basecaller, dorado, and I…
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Hi,
only m6A can be detected by Remora? Do you have any plan to add more models for other types of modifications on RNAs?
Best,