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# Increasing the Realism of Our Simulations
One research question we want to address in this project is: **Are true trees categorically different from MP trees in a predictable way?** If the answer…
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Hi,
Which parameters should I use to detect somatic hypermutation (SHM) in the command "mixcr analyze exome-seq".
or can I use "mixcr analyze exome-seq" to detect somatic hypermutation (SHM).
…
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Let's make a collection of real projects build with Iced.
## Projects
### Airshipper ([Repo](https://github.com/Songtronix/Airshipper))
Video game launcher
- Client / server desktop app
…
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Hello,
I have a question about how the VDJs are assigned to the contigs.
I have a trust4_cdr3.out, and I can see for example for malignant cells in my data, there are multiple VDJs. How is this po…
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Hello,
I'm mucking about with the various intermediate files, as sometimes it's desirable to look at variably incomplete contigs. From my understanding, `annot.fa` is a master list of "raw" contigs…
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Hi Quentin @qmarcou,
I am a new bioinformatics postdoc in Prof. Frederick Alt's lab. I have read your 2018 Nature Communication paper introducing the fantastic tool IGoR, and I am now trying to app…
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Hello,
I had a question regarding the MiXCR's defaut library reference sequences. I noticed there were some differences in terms of list of alleles for specific v genes and what v genes were inclu…
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Hi,
Sorry for spamming the issues. I am having an error come up whenever I try to add a whitelist.
essentially the run report gives me no additional explanation other than:
failed: 11 at run…
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Hi,
SigProfilerExtractor is really handy. It has helped me a lot.
However, I have a question about input samples. Do we need to delete hypermutation samples? Will samples with too many mutations …
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Hi,
I'm new to huggingface and gatortron. I wish to generate text from a medical description for example, but not sure how to do it with the gatortron models. I've tried to adapt other examples (e.…