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Hello,
We are trying to use MCP counter on mouse bulk RNA seq data.
First we tried mMCPcounter, however we encountered issues with their given signature.
So, next, we tried MCPcounter. We ha…
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Goal: The goal of this issue is to create unit tests for high-throughput transcriptomics (HTTR) signature data such that we ensure that as the codebase of tcplfit2 is updated that the updates do not b…
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Hello,
I am trying to use xCell with Proteomics data, before using it I normalized and imputed the data. I also checked the number of genes, the tool requires minimum 5000 genes, my file contains …
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because of the reasons discussed...
I'm not sure what should be the default behavior, though. But taking all genes as background could result in misleading results and significant 'over-estimation'…
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> Background
> The drug discovery and development pipeline is a long and arduous process that inevitably hampers rapid drug development. Therefore, strategies to improve the efficiency of drug develo…
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hi developer, thank you so much for your helpful tools.
I tried to use irGSEA to calculate the GO -BP geneset enrichment scores. But when I calculated the enrichment score as shown below:
`skin.GO.B…
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Hi authors,
I saw it in the paper that you are using positional gene sets, motif gene sets and immunological signatures as features. I wonder how you put three dataset into one list. Additionally, …
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Hi,
Ly6g is a good mouse neutrophil marker (therefore probably will be included in the gmt file neutrophil signature).
I noticed that this gene is missing in besca/datasets/homologs/MGItoHGNC.csv…
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While running sc.metabolism.Seurat function, I encountered an error in "Computing differential signature tests..." step.
It mentioned that Error in `[dense coercion: allocating vector of size 3.1 Gi…
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Found a couple of small bugs in CreateBigSingleRObject, but they caused a lot of issues for me. Default parameter min.genes was set to 200, whereas in CreateSinglerObject min.genes was set to 0. This …