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I run strelka2 version 2.9.10 with paired normal-tumor somatic mode, and got an site which indicated that it should be LOH type.
1 241663871 . G A . LowEVS SOMA…
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### Description
Clinicians need to be able to detect LoH and CNV in TGA cases. Currently a CNV report is produced which contains diagrams and tables for CNVs and LoH, CNVs are also in the SV VCF file…
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Hi, I have a quetion about removing cnv like noise
First, I use Run_numbat(function) with option like this
`
out = run_numbat(
count_mat, # gene x cell integer UMI count matrix
ref_h…
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**Description**:
When using `AddPicture` or `AddPictureAsync` in EPPlus, the method generates a significant amount of Large Object Heap (LOH) memory, which can lead to performance issues, especiall…
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ImageSharp's default configuration pools image buffers. The problem is that it will happily keep large LOH buffers around which is quite a waste of memory usage. We should investigate what can be done…
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I ran Canvas Germline-WGS for several samples and all have lots of LOH variants (I consider only PASS variants.) For example, Illumina's .SV.vcf.gz for a sample has only one LOH:
16 GAIN
1 LOH
17 L…
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**Getting below error in runCaSpER function:**
**object
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Take this segments.tsv for illustration, where both segments are > 10Mbp and display different copy number counts but same lohtype:
chr start end copy_number lohtype
1 752001 168…
ghost updated
5 years ago
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![image](https://github.com/dotnet/roslyn/assets/31348972/df661568-2505-4345-b27e-0135e26d126c)
Found these LOH allocations in devenv process.
Same trace as for https://github.com/dotnet/roslyn/…