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Hi there!
I've been interested in estimating the contribution of mutational signatures defined originally with whole-genome data to variant calls from panels such as MSK-IMPACT ; I wonder what the…
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Hi,
I have been running Palimpsest on mutations in whole genome and same mutations but falling in specific regions of the genome. I observed that in these two different runs, same mutations annotat…
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Quick question here regarding extending TrackSig beyond the hg19 reference build. In src/getMutationTypes.pl, line 16 has the explicit delineation of using hg19:
my %fastaHandles = ("path" => "annota…
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Dear @huebschm ,
I want to cite your software package _YAPSA_ for my paper. But since the journal of interest requires me to include **the paper or preprint of the software package** into the refer…
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Hello
I was wondering if DISCOVER is suitable for samples with high mutation rates (e.g. skin tumour samples with UV mutational signatures; ~5-10 mutations/Mb). I have a cohort that seems to have T…
kw10 updated
11 months ago
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Currently, for MSK IMPACT, we have mutations, CNAs and fusions/SVs, but we have many additional types of derived data generated by CMO.
- Mutational signatures
- HLA types
- HLA LOH
- Genomics-i…
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https://doi.org/10.1126/science.abl9283
Please keep this checklist for curation of a new study.
- [ ] [create an issue on datahub](https://github.com/cBioPortal/datahub/issues/new) before curati…
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Please keep this checklist for curation of a new study.
- [ ] [create an issue on datahub](https://github.com/cBioPortal/datahub/issues/new) before curating a study (one issue per study) and copy t…
jjgao updated
2 years ago
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Reference: Fig 2 Part 1 (pg 31) of Alexandrov 2018 "The Repertoire of Mutational Signatures in Human Cancer" http://dx.doi.org/10.1101/322859.
- Rows are signatures (as in SBS plot) (the referenc…
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Hi Renaud,
I'm trying to reproduce a clustering similar to the one described in [this paper](http://www.sciencedirect.com/science/article/pii/S2211124712004330). I believe that the first part of thei…