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I suggest to compare MEDIC and MONDO. Reviewers might bring this up anyway.
http://ctdbase.org/downloads/#alldiseases
drseb updated
7 years ago
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Hi,
Thanks for the helpful package! I was wondering if there is a way that I can change the dots into vertical lines on the manhattan plot? (Making it more like a histogram and less like a scatter…
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I think we need to multiply the kinship matrix by a factor of 2 in `scan1()` and related functions. For example, see equations 4 and 5 in [Almasy and Blangero (1998) Multipoint Quantitative-Trait Link…
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@zanyzooks is thinking about this
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Nik made a good point to look at the source of error (u). If it's caused by different genetic background or something of that nature mediating the expression, we should be able to analyze it by lookin…
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Currently (0.11-1) the function is integrated within `remlf90()`
1. Take it out as a separate function. It only depends on the result of `pf90()`.
2. Unit test it
3. Allow for multiple genetic effects…
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Hi,
The link for the list of HapMap3 SNPs under Part 1 of the Partitioned Heritability page (https://github.com/bulik/ldsc/wiki/Partitioned-Heritability) isn't working for me. The following error co…
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The following reproduces the error using breedR's globulus dataset:
``` R
packageVersion('breedR') # 0.11.1
res Error : sum(idx
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Near the top of 'Heritability and Genetic Correlation', there is a command just after _"If you just want to compute heritability and the LD Score regression intercept, replace the last two commands wi…
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Hi,
I am using the LD Score Regression method to compute the genetic correlation between two different phenotypes in patients from European ancestry (using summary statistic data). I have noticed so…