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Hi Oliver,
I am trying to construct GeRS using the method you described in your paper _Imputed gene expression risk scores: a functionally informed component of polygenic risk_ published on _**Huma…
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Hello,
I'm writing to you because I'd like to know if it is possible to use PRSice-2 without knowing the phenotype. In my case, I'd like to calculate COVID-19 Polygenic Risk Scores. Firstly, I obtain…
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In #52 we added the ``sim_trait(ts, num_causal)`` function which returns a pandas data frame with num_causal rows. It seems to me that we will often want to simulate multiple traits, which perhaps we …
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### Description of the bug
Input bed file is not found, but exists. Command, samplesheet, output, .nextflow.log, and .command.run are provided below.
### Command used and terminal output
```console…
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Hi,
I'm trying to run my first polygenic risk scores using PGS catalog. But I found an issue. I copy the error code below. I think the problem that I have, involves the preparation of my input gen…
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### Description of the bug
It looks like the workflow is trying to access the "NO_FILE" placeholder as if it were a real file, leading to a NoSuchFileException, and then:
> ERROR: No results repor…
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Hi Florian,
Hope you are doing well!
I am currently working on a project that involves the calculation of polygenic scores of multiple traits by LDpred2 for prediction.
However, external GWA…
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貼吧活動:(請查閱 [SARS-CoV-2 Timeline by 2020.02.21](https://github.com/agorahub/_meta/blob/agoran/theagora/sari/Memorandum_2020-02-21_SARS-CoV-2-Timeline_Nathan.pdf?raw=true), by Nathan :cloud: )
- Colla…
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### Description of the bug
**The bug:**
I get an error "pgscatalog_utils.samplesheet.check: 2023-09-12 23:19:30 CRITICAL /home/ec2-user/data/test_data/KGH2.vcf.gz doesn't exist, please check sampl…
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Dear Authors,
We are using LDpred2 in bigsnpr to estimate weights to generate polygenic risk scores. Here, we note the much lower than expected correlations between weights generated using different …