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R190S is becoming very convergent with 31del lineages. There's at least 10 each separate emergences of this under LB.1 and KP.2.3, and many emerging under KP.3.1.1.
From branch 12 of https://gith…
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KR.1 got its DeFLiRT sublineage likely in Philippines
Defining mutations: KR.1 >> C6568T > C6388T, S:S31del (del21653-55)
(New) Query: C6568T,C6388T,T3565C,C897A (by @aviczhl2 )
Samples: 3
Countr…
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There seem to be several people in the introductions thread (#17 ) who are interested in zoonotic diseases, a topic that is currently missing from [the introduction section outline](greenelab/covid19-…
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I noticed a strange bug with the version history for EBI-UniProtKB NT files. On the sample view page for the dataset, when you select different version histories using the drop down, after the second …
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We received the 9 purchased analogues of the original hit [RA-0020084-01](https://github.com/StructuralGenomicsConsortium/CNP27-SARS-CoV-2-NSP14/assets/133207721/a706fd3c-0d56-488e-9eb6-9a1d7b4ce325) …
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We received the 8 purchased analogues of the original hit #2: [RA-0020083-01](https://github.com/StructuralGenomicsConsortium/CNP27-SARS-CoV-2-NSP14/assets/133207721/4df27ee7-dd09-4cfb-b4a6-b43c6f4651…
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- Convincing active hits against SARS-CoV-2 helicase remain elusive despite attempts from many groups and organisations.
- Zhou et al. (2024) https://doi.org/10.1038/s41557-024-01442-y published …
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From branch 58 of https://github.com/sars-cov-2-variants/lineage-proposals/issues/1253
JN.1+C16269A+C12781T+S:F456L
Query: G16269A,C12781T,T22928C,G22599C
No. of seqs: 12 (Canada 3 UK 1 USA 8)
Fir…
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**Resources:**
- LOINC pre-released COVID-19 related terms:
https://loinc.org/sars-coronavirus-2/
- FDA EUA authorized IVD tests:
https://www.fda.gov/medical-devices/emergency-situations-medi…
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### A summary and discussion of the 19F NMR fragment screen approach towards the SARS-CoV-2 helicase, Nsp13.
### Current Objectives as of 11th March 2024:
**@TomkUCL:**
- [x] 1. Synthesis…