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```
$ nextflow run pgscatalog/pgsc_calc -latest -profile test,singularity
...
Pulling Singularity image
oras://dockerhub.ebi.ac.uk/gdp-public/pgsc_calc/singularity/pgscatalog_utils:amd64-0.3.…
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Dear Florian!
I have a question related to controlling for covariates. For my analyses, I’m using a GWAS summary statistic where age, gender, and 10 principal components were added as covariates in t…
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Hi Florian,
I am trying to adapt one of your tutorials to my data set:
https://github.com/privefl/paper-infer/blob/main/code/example-with-provided-LD.R
For now I cannot have my genotypes combin…
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**Describe the bug**
The versions of the `ldpred2.R` and `createBackingFile.R` scripts from the main branch to a MoBa sample/height phenotype, the predicted scores do not correlate with the phenotype…
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Dear Dr. Prive
Thanks for your great tool LDpred2!
I am learning to use it to calculate PRS, but encountered some questions. Can you help me out ? Thanks!
1, on your webpage https://privefl.g…
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Hello Dr. Privé,
I am trying to generate polygenic risk scores with LDpred2's automatic model and have encountered some problems. I have got LDpred2 running without error and produced a set of resu…
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Dear Florian,
Our group is using LDpred2 for the development of polygenic scores. After obtaining lower than expected results, we have tried to simulate the results of the paper with the summary s…
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Hi Sam @choishingwan ,
When we compare LDpred and Lassosum, we see that SNP's matching is used in the LDpred, but it is not used in the Lassosum. Would you please explain if there is any possible r…
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I am getting an error and wanted to check with you if what I am observing is an error or intentional design. When all the phenotypes for the samples in my fam file are NA, I get "No phenotype presente…
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Dear Tian,
First,Thank you for your valuable tool for PRS analysis. It really helps me a lot.
I'm new to the genetics. May I ask the key follow-up parts, such as how the results built using your…