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the data from https://www.biorxiv.org/content/early/2014/09/04/008797 is in http://www-personal.umich.edu/~xwen/geuvadis/
an overview of the full project: http://www.geuvadis.org/web/geuvadis/RNAse…
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https://mp.weixin.qq.com/s/xuR5R8DDqoe1nydrQgTTrg
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Input:
- GENCODE
- PacBio isoforms (with ORFs predicted) for osteoblasts
- sQTLs for a GTEx tissue
Output:
- Table of each sQTL and several categories (base to detailed) of the effect on protei…
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Are there any plans to migrate fusion_twas to use GRCh38 and version 8 of GTEx?
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Hi
When I used the nominal pass to call sQTLs, I found that there were a lot of repeat sQTLs in the output file named XXX.nominal.XX (example in the below). Can you give me some ideas about this issu…
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Dear hyprcoloc team,
I would like to run hyprcoloc analysis using GWAS, eqtl and sqtl data. I have generated the file with beta columns for a list of variants for each dataset. My question is wheth…
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https://mp.weixin.qq.com/s/67XcexbMJnIy6-GyI8OwzQ
ixxmu updated
2 years ago
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Currently testing all SNPs within a megabase either side of gene TSS. This is unnecessary and leads to huge summary stat files and potentially lots of spurious colocalisations.
This will require ha…
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Hi,
In the sMultixcan output using GTEx v8 sQTL database, the gene names are encoded as 'intron_chromosome_start_end'. How can we link this back to the gene symbol?
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Complex genes will have multiple splicing clusters within them. In theory each cluster could have independent cis genetic regulation.
Therefore add an option in sQTL mapping to either group QTLs by…