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Hi,
I'm having issues trying to run SigProfiler for CNV data using custom CNV calls. We have an in-house pipeline for CNV calls that is similar to the ASCAT approach, tailored to our WGS data. I t…
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Hi @ShixiangWang,
Hope you're well.
Just noticed that when using the sig_tally() function with the Wang method, the row names in the resulting NMF matrix (tally_wang$nmf_matrix) are unexpectedly…
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Add 3.3 and 3.4 COSMIC copynumber CN48 signatures to database
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Hello, when using Sigminer for CNV (Copy Number Variation) and SV (Structural Variation) signature analysis, the selection allows me to choose n signatures. How are the confidence scores of these sign…
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https://mp.weixin.qq.com/s/Oq_SUfuoaa6x0zt4y3jEPg
ixxmu updated
7 months ago
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https://mp.weixin.qq.com/s/zttX7tKl9uVPLtHrXqmRYg
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Thank you for this great package! I have been following the documentation and performed CNV signature extraction using the Wang method. I am wondering if there is a method to make sense of extracted C…
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Hi,
Many thanks for this tool!
I am using sigminer to identify copy number signatures from segmented data, and I would like to account for the gender of the samples to do so.
In this case I thin…
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Hello
I am interested to plots in this copy number part
https://shixiangwang.github.io/sigminer-doc/cnobject.html
But I am not quite sure where I can find `cn` example input to prepare my own…
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Use data from Chen's original paper or placenta data. Get clarifying information from Steven.