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Preferred Term: single-nucleus methylcytosine and transcriptome sequencing assay
Synonyms: snmCT-seq
Definition: A multiomic method to measure the cytosine DNA methylation and gene expression signat…
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We know we are moving forward with RNA-seq, and I think it would be beneficial to rank priorities on other analyses:
Here is a non exhaustive ranked list to start with but would like to get more op…
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Talking with Dr.Sun to ensure the research topic, read the paper "DNA methylation analysis explores the molecular basis of plasma cell-free DNA fragmentation. Nature Communications, 14(287), https://d…
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(Please excuse my amateur approach to this I am relatively new to this viewer!)
I was wondering if anyone could help me out with quantifying DNA Methylation on IGV when you are comparing two file…
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Hi,
Can we use differential methylated region file (attached) as input for omicsintegrator ? I gave it a try but its writing one chromosome several times in the events_to_genes file (attached). Is…
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Thank you for developing this amazing tool. I am wondering if there is a way to simulate reads with DNA methylation signals. If not, do you have any plan to include the function in the near future? Th…
xies4 updated
4 months ago
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I think I get where the modification probabilities are coming from (ML values / 256). But if I pass a filter that's being used for both modified and canonical calls, where does the canonical base prob…
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Sam Bogan Review of “DNA Methylation Analyses” by Steven Roberts, Sam White, and Yaamini Venkataraman
link: https://d.pr/f/332Q5v
Original text is in blue. Suggested text is in red.
General Feedb…
sr320 updated
6 months ago
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GO:0044030 regulation of DNA methylation
GO:1905642 negative regulation of DNA methylation
GO:1905643 positive regulation of DNA methylation
Annotations are here: https://docs.google.com/spread…
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Dear author
I'd like to ask you a question,I used megalodon to call methylation and found that in the centromeric region, it showed a hypomethylation state,which corresponds to the peak of CHIP,Thi…