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Hi,
I am interested in studying protein-nucleic acid couplings, like that of transcription factors and RNA binding proteins. I was looking at the plmc script and was wondering how I should go about…
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**Lab Name**: Bioinformatics and Data Science in Biotechnology Lab
**Department**: Biotechnology and Biomedical Engineering
**List of Experiments and Repositories**:
1: Writing and…
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I have a set of nucleotide sequences and I need the pairwise sequence similarity of all vs all.
I understand that one should create a fake_pref and use it to run mmseqs align. Yet, in the document…
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# Background
The JnJ team requested using [Mafft](https://mafft.cbrc.jp/alignment/server/index.html) for DNA/RNA sequence alignment.
# Scope of work
* Implement running MSA via Mafft
* Add UI to…
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### Description of feature
The current stop-codon detection in ampliseq could be improved and supplemented with frame-shift detection by implementing [MACSE](https://doi.org/10.1093/molbev/msy159). T…
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I'd like to ask if it would be possible to support the alignment of DNA sequences using the C API? I would like to integrate `block-aligner` into an existing C/C++ tool but cannot use the exisiting C …
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## Bug Report
### Affected tool(s)
_picard ValidateSameFile_
### Affected version(s)
- [x] Latest public release version [3.1.1]
- [ ] Latest development/master branch (not tested)
### Des…
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Thank you for your excellent work! We know that the parameter 'blastx' can be used for DNA alignment. We have no idea if a DNA sequence can not be translated into protein sequence, can Diamond still …
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Hi Sungsik,
Thank you for creating this program. I would love to try it out but I am having some troubles uploading my sequential phylip file.
Here is what the first few lines look like.
86 …
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Hi,
Thanks for your work with clair3!
We are running clair3 v1.0.9 via docker and we encountered an expected result that we would like your opinion about.
We have a previously known and vali…