monarch-initiative SLDBGen issues

monarch-initiative / SLDBGen

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bring develop up to date

#207 pnrobinson closed 2 years ago
0
A transform to produce KGX tsv

#206 caufieldjh closed 2 years ago
0
Develop

#205 pnrobinson closed 2 years ago
0
Develop

#204 pnrobinson closed 2 years ago
0
Synthetic lethality guiding selection of drug combinations in ovarian cancer

#203 pnrobinson closed 2 years ago
1
Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens

#202 pnrobinson closed 2 years ago
1
Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma

#201 pnrobinson closed 2 years ago
1
Synonymous entries in column 'cell.line'

#200 hansenp closed 2 years ago
1
Incorrect entries in column for assays

#199 hansenp closed 2 years ago
1
ValueError: Could not find id for gene CDR1 in Steckel 2012

#198 hansenp closed 2 years ago
8
Develop

#197 pnrobinson closed 3 years ago
0
CYP2S1 is a synthetic lethal target in BRAF V600E-driven thyroid cancers

#196 pnrobinson closed 3 years ago
1
Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis

#195 pnrobinson closed 3 years ago
1
Inhibition of poly(ADP-ribose) polymerase induces synthetic lethality in BRIP1 deficient ovarian epithelial cells

#194 pnrobinson closed 3 years ago
1
Synthetic Lethal Interactions of RECQ Helicases

#193 pnrobinson closed 3 years ago
1
The CINs of Polo-Like Kinase 1 in Cancer

#192 pnrobinson closed 3 years ago
1
A Novel cytarabine analog evokes synthetic lethality by targeting MK2 in p53-deficient cancer cells

#191 pnrobinson closed 2 years ago
1
WDHD1 is essential for the survival of PTEN-inactive triple-negative breast cancer

#190 pnrobinson closed 3 years ago
1
Integrative omics analysis reveals relationships of genes with synthetic lethal interactions through a pan-cancer analysis

#189 pnrobinson closed 2 years ago
1
Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression

#188 pnrobinson closed 3 years ago
1
Recombination and Pol ζ Rescue Defective DNA Replication upon Impaired CMG Helicase-Pol ε Interaction

#187 pnrobinson closed 3 years ago
1
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q

#186 pnrobinson closed 3 years ago
1
XRCC1 deficient triple negative breast cancers are sensitive to ATR, ATM and Wee1 inhibitor either alone or in combination with olaparib

#185 pnrobinson closed 3 years ago
1
Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1

#184 pnrobinson closed 3 years ago
1
Synthetic Lethal Screens Reveal Co-Targeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma

#183 pnrobinson closed 3 years ago
1
Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells

#182 pnrobinson closed 3 years ago
1
first pass at schema

#181 cmungall closed 3 years ago
0
XRN2 interactome reveals its synthetic lethal relationship with PARP1 inhibition

#180 pnrobinson closed 3 years ago
1
Summary

#179 pnrobinson closed 3 years ago
4
Cohesin mutations are synthetic lethal with stimulation of WNT signaling

#178 pnrobinson closed 3 years ago
1
Develop

#177 pnrobinson closed 4 years ago
0
Code fixes

#176 pnrobinson closed 4 years ago
2
Code fixes

#175 pnrobinson closed 4 years ago
0
check and remove self-loops

#174 pnrobinson closed 4 years ago
1
Missing "NCBIGene:" for some SLIs

#173 pnrobinson closed 4 years ago
2
Integration of multiple biological contexts reveals principles of synthetic lethality that affect reproducibility

#172 pnrobinson closed 2 years ago
1
Dual Targeting of PDGFRα and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors

#171 pnrobinson closed 4 years ago
1
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma

#170 pnrobinson closed 4 years ago
1
Phospho-ERK is a biomarker of response to a synthetic lethal drug combination of sorafenib and MEK inhibition in liver cancer

#169 pnrobinson closed 4 years ago
1
RAF dimer inhibition enhances the antitumor activity of MEK inhibitors in K-RAS mutant tumors

#168 pnrobinson closed 4 years ago
1
Synergistic Interaction of Histone Deacetylase 6- and MEK-Inhibitors in Castration-Resistant Prostate Cancer Cells

#167 pnrobinson closed 4 years ago
1
XRN2 interactome reveals its synthetic lethal relationship with PARP1 inhibition

#166 pnrobinson closed 4 years ago
1
Develop

#165 pnrobinson closed 4 years ago
0
Develop

#164 pnrobinson closed 4 years ago
0
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

#163 pnrobinson closed 4 years ago
2
Synthetic Lethal Screen of an EGFR-Centered Network to Improve Targeted Therapies

#162 pnrobinson closed 4 years ago
3
Develop

#161 pnrobinson closed 4 years ago
0
A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer

#160 pnrobinson closed 4 years ago
1
Systematic Identification of Molecular Subtype-Selective Vulnerabilities in Non-Small-Cell Lung Cancer

#159 pnrobinson closed 4 years ago
0
Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells

#158 pnrobinson closed 4 years ago
1