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CIViC (Clinical Interpretation of Variants in Cancer) is an open-access, community-driven resource for the clinical interpretation of cancer variants. To enhance Scout’s functionality for somatic vari…
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Hi,
I noticed that the pipeline detects some somatic mutations with VAF = 1 in a specific cell type. Such mutations may be an example of cell-type-specific clonal expansion which may not be true so…
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[Placeholder for implementing a tier based ranking for somatic mutation]
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### Resources
Resources needed to be able to understand and implement a tier based ranking
#### Publications
What …
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### Description of feature
Hello, thanks for the great work with this pipeline. I would like to try to use this pipeline to call somatic mutations in single cell rna-seq data. I have my own WGS refer…
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In the context of somatic mutations there is no easy way to represent a genotype in the same way as in germline variants. For this reason, some somatic mutation callers, do not provide genotype inform…
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Hello,
Any tutorial on paired normal-tumor somatic mutation calling?
Thanks
Jim
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Hi @reimand0 ,
I am getting an error, when trying to run ActiveDriveWGS using following command:
```
ActiveDriverWGS.res[[i]] = ActiveDriverWGS(mutations = ActiveDriverWGSInfo[[i]], elements = …
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Hi! Dr. Dou,
Thank you for developing this great software Monopogen for both germline and somatic SNVs detection in single-cell sequencing data. We found it very efficient in somatic mutations call…
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Issue by @MaxUlysse, moved from SciLifeLab#666
- [ ] [ExpansionHunter](https://github.com/Illumina/ExpansionHunter) for estimating repeat sizes
- [ ] [QDNAseq](https://github.com/ccagc/QDNAseq) CN…
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A recent Nature [article](http://www.nature.com/nature/journal/vaop/ncurrent/full/nature16965.html) on pancreatic cancer sequenced 382 patients from the Australian Pancreatic Cancer Genome Initiative …