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We currently use the formula: `alt reads / read depth` but a user asked if we shouldn't instead use `alt reads / (ref reads + alt reads`).
Please note that the e formulas can return very different …
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Request to have the same feature as in MIP/SCOUT where all possibly compound variants are uploaded when looking at one variant. Including VAF-data....
![image](https://user-images.githubusercontent…
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Hi I want to filter low VAF from the benchmark vcf file. This is the link to the vcf https://ftp-trace.ncbi.nlm.nih.gov/ReferenceSamples/giab/release/NA12878_HG001/latest/GRCh38/
How can I calculat…
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We need to have a VAF field present from DeepVariant in a pVCF generated by GLnexus. Is it possible to adjust .yaml file to also include the original VAF field into the pVCF ?
Thanks!
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Currently we just parse out the reads that Pindel calls, it would be nice to evaluate that an event has no normal support and then run ssearch36 over reads in the primary BAM to generate an accurate V…
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Hi, thanks for your great work. Do you now support loading the variant from vcf files and filter the variants based on vaf, dp, dq, etc? Thanks a lot.
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Hi,
I have created an input for addSV in which there are deletions with different VAFs (0.6, 0.9 etc.). However, in the final VCF all DEL are with VAF 1 meaning that all reads are deleted. Could y…
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Hello guys,
I found a extrange behaviour trying to translate a word:
```python
from urllib.parse import urlencode
import requests
def translate_to_and(sentence, vaf):
encoded_…
ssoto updated
3 years ago
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Hi,
I used SVision-pro to call somatic SVs, but the number of somatic SVs identified is relatively low, only around 500. In comparison, when using pbsv, the number is over 5000. Is it normal?
Be…
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This post details how to correct VAF to CCF, including confidence intervals. I should implement this method for the shiny interface.
https://www.biostars.org/p/6368/