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Hi!
First off, thank you for this analysis tool!
I am analyzing some Perturb-Seq data and have followed the vignette. I ran Mixscale_Scatterplot and interestingly the perturbation score seems p…
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GO:0000120 RNA polymerase I transcription factor complex
A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase I.
I have
+ RNA polymerase I …
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Hi,
When looking at the results of calculating ananse influence over two networks, we (in the lab) have noticed that none of the factors in the output have a negative logFoldChange (meaning, only f…
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https://doi.org/10.1038/ncb2709
# Authors
Moignard, V., Macaulay, I.C., Swiers, G., Buettner, F., Schütte, J., Calero-Nieto, F.J., Kinston, S., Joshi, A., Hannah, R., Theis, F.J., Jacobsen, S.E.…
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How should we approach this dataset?
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Identify at least 2, ideally 3 alternative methods that can use prior information (known targets of transcription factors) to predict TF activities on single-cell transcriptomic profiles.
These met…
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Thank you so much for developing the tool!
I would like to know if in the LR-TF database you collected, are all LR's effects on TF activated? Is it possible that LR's effect on TF is inhibitory?
…
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Hi,
I am interested in studying protein-nucleic acid couplings, like that of transcription factors and RNA binding proteins. I was looking at the plmc script and was wondering how I should go about…
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Hello,
I am trying to vizualize my results of enrichment with a dotplot with the code below :
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query