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**Transferred from:** [NIF-11673](https://support.crbs.ucsd.edu/browse/NIF-11673)
**Original Reporter:** Nicole Washington
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We need to expand the genetic heritability subclasses to include:
X- Y…
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# Heritability (1): How 'genetic' is a trait? | Arslan Zaidi
One of the reasons I’ve come to write about this is because recently I’ve been asked a lot about “how genetic is this trait or that trait?…
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Allow extension of trios to at least grandparents to observe heritability
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Dear BHR team,
Thanks for previously helping diagnose the issue regarding burden correlation function! Now I met a new issue when analyzing the heritability of my traits.
As mentioned in the pap…
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I am using ldsc to compute the genetic correlation between two traits. However, the heritability estimates in the process of computing is different from heritability computed using --h2. have compute…
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Hello, thank you for the nice work. I am trying to run GENESIS on a few GWASs, and I am a bit confused with some of the parameter setting:
1) the input should includes the effective sample size, de…
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Hi,
When I executed remlf90(), I obtained following results:
Variance components:
Estimated variances S.E.
genetic 1.844e-05 0.006452
Residual 3.721e+02 27…
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Hi,
When I did the prtitioned heritability with 1000G_Phase3_baselineLD_v2.2_ldscores.tgz, the Prop._h2 was negative and it was very significant. Is this a bug?
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I am trying to run my own data on SUPERGNOVA,
however, I get the following error when testing:
Preparing files for analysis...
Calculating LD scores...
49351 SNPs included in our analysis...
C…
liym9 updated
8 months ago
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I am trying to run `ldsc.py` to measure enrichment of GWAS risk variants in open chromatin regions of interest. I have generated the thinned `*.annot.gz` files for these regions and computed the LD sc…