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I'm trying to simulate clonal evolution with mutation and selection. I set up some extreme values to test the code.
```python
s=1
h=1
Nloci=4
mu=0.001
popsize=10
maxgen=2000
import simuPOP a…
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https://mp.weixin.qq.com/s/shwo8FpaCNZ0hCPIqsAzkQ
ixxmu updated
8 months ago
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Hello,
This is a .out file from run_numbat:
`Loading required package: Matrix
Registered S3 methods overwritten by 'treeio':
method from
MRCA.phylo tidytree
MR…
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New projects (5):
1. [Cellular development and evolution of the mammalian cerebellum](https://data.humancellatlas.org/explore/projects/279f1766-3319-4e3c-9f99-6fb59ba9b3e5)
1. [Dysregulated lung…
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Hello, I am interested in trying pair tree and I have some questions regarding the SSM input file generation.
In the input SSM file under the var_read_prob column. I understand that this is the pr…
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Hi Nick,
have you thought about implementing phylogenetic trees? I think this could be quite useful in many situations.
Ideally, I envision tracing clonal evolution using information from TCR/BCR …
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Hello,
I'm investigating a dataset of Streptococcus iniae species comprising around 80 bacteria, split into two distinct lineages (79 in one lineage and 1 in the other). Despite being isolated from…
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Good morning,
Would you please provide some details about how two functions "clonalHomeostasis" and "clonalProportion" per sample and per seurat clusters, are working?
Thanks!
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貼吧活動：(請查閱 [SARS-CoV-2 Timeline by 2020.02.21](https://github.com/agorahub/_meta/blob/agoran/theagora/sari/Memorandum_2020-02-21_SARS-CoV-2-Timeline_Nathan.pdf?raw=true), by Nathan :cloud: )
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Hello
I am working on a clonal organism but we believe more and more it might not be so clonal. We have HiFi data and I want to use them to detect MAF. Is it possible with DeepVariant to detect tha…