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The code attempts a `full join` here:
https://github.com/cruk-mi/mesa/blob/212a791cb4da2d2d2c099c4ef53b4b71d5f1ee65/R/combineQsets.R#L193
But, when joining large `qseaSets`, the result is too mu…
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http://doi.org/10.1038/srep19598
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Dear Raymond,
Thank you for your previous help on "input methylRaw object #46": methyldacker works very good and fast for us!
I'm sorry but we need again your help!
We have done the analysis for DM…
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How genetic variations and epigenetic dynamics contribute to normal biological function and disease processes[^1].
Teamwork is a significant part of science. When the right group people who have uniq…
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Hi,
I'm testing this pipeline on some EM-seq samples we have recently generated and getting following error with TSS_cpg_bins.py
File "/Software/EM-seq/TSS_cpg_bins.py", line 254, in
normal_…
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Hi,
I know Nanopolish can output both tsv and modified bam when calling methylation but I wondered if you had (or knew of any) available scripts that would convert modified bam files into the Nanop…
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I ran this code to use the modsites-mode
aligned_bam_to_cpg_scores \
--bam ${f}haplotagged.bam \
--threads 8 \
--modsites-mode reference \
--ref /home/wdmays/coccolith_datasets/reference…
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Hi,
Thank you for your hard work!
I get 24 available age clocks using the availableClock() function, but README.md only mentions 16. Could you kindly provide me with all the published informatio…
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Hi,
I am looking into 6mA methylation and I have done a locus plot for 6mA at the the AT motif.
I just want to clarity the genome-CpG plot on the locus plots - does this therefore represent ge…
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Hi,
I'm a big fan of `bsseq` because it is exactly the data structure I need for a package I maintain (`methylSig`) that tests for differential methylation (at CpGs and over regions).
As of the …