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is the structural equation modeling for continuous variable same as for binary or ordinal variable when heritability is estimated? are the paths different between the two types of variables?
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Hello,
When using variable selection method on markers, how do you calculate variance explained both genetic and phenotypic of all snps? I tried to follow the example in vignette but I am getting a…
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We are interested in your method MonsterLM to estimate GxE heritability. It stands out in the field for its innovative approach and its consideration of noise heterogeneity, demonstrating scalability …
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I wanted to estimate genetic correlation between two binary trait, The summary statistics beta and se are based logistic regression. Their Zscores range are [-8.881,7.614], and [-4.398,5.029]. When I…
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Category | Prop._SNPs | Prop._h2 | Prop._h2_std_error | Enrichment | Enrichment_std_error | Enrichment_p | Coefficient | Coefficient_std_error | Coefficient_z-score | Coefficient p-value
-- | -- | …
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Hi there, I keep getting an error for partitioned heritability. I've tried multiple different combinations of files (including the suggested ones in the tutorial) and with or without merging with hm3…
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Hi,
does anyone know, what could be wrong when I receive this error message:
Reading annot matrix from ----/Filtered_baseline.[1-22] ...
Traceback (most recent call last):
File ".../ldsc/lds…
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Recently, I have been trying to use LD regression to estimate heritability for each allele frequency range in my data. I read the tutorial from github and understand that I need to calculate partition…
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Heritability and Genetic Correlation Tutorial on:
https://github.com/bulik/ldsc/wiki/Heritability-and-Genetic-Correlation
Data required to be downloaded using:
wget www.med.unc.edu/pgc/files/resu…
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Hi, I am trying to use your software to calculate the genetic correlation between phenotype1 and phenotype2, but the estimated heritability of phenotype1 is negative, thus I cannot get the genetic cor…