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I am working with very small fixed regions so any tiny differences should give large accuracy errors, but despite that, I am finding matches with very high confidence levels. The attached two images …
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Hi,
Thank you for this great tool.
I have a question with regard to SNV calling in paraloguous regions for WES/WGS illumina models.
As i understand, by default, candidates variants in regions with …
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Hi,
I have recently been using Model-Angelo to identify an unknown density determined by cryo-EM with a local resolution of about 4 Å. I'm uncertain whether this region belongs to RNA or protein. Des…
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Gold standard benchmarking datasets such as the GIAB/NIST NA12878 and the Illumina Platinum Genomes truth sets provide both a VCF containing the variant records themselves, plus a BED file of "high co…
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Hi @marcotcr, whilst browsing the repo I noticed that you've removed the bisection part for computing the upper and lower confidence bounds: https://github.com/marcotcr/anchor/commit/ff0924e6bcaaa7149…
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Similar to #11 I'd like to make my decoil ecDNA calls more conservative. But most of my samples have ~25-30x and I don't want to downsample them and loose information unnecessarily.
With default…
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Hi,
I have a question.
My plan is to provide the mtracker.Update method with custom regions.
I am generating my regions with the following:
```
new_regions = []
for el in orig_regions:
…
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Thanks for sharing your great work.
I'm encountering an issue with outdoor shots that show the sky. Some frames will place the sky in the foreground and some will not, causing huge temporal incons…
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Room having bright windows tends to have infinite depth, hence non-desirable results. Any workaround?
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Dear Chai Discovery Team,
First of all, I want to express my gratitude for making the Chai-1 codebase open-source and accessible to the community. Your work is truly invaluable and has great potent…