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Hello,
Thank you for sharing this excellent project. I am currently trying to run the project, but I am having some difficulties regarding the test data and data preparation methods for zero-shot pre…
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Thank you for this great work. I learned a lot of insights of alphafold from openfold paper.
I am predicting antibody-antigen complex. In my case, I already know the structure of Ab-Ag complex, …
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Dear pVACtools authors,
Thank you so much for the impressive work. We have used the tools in many of our analyses. We are now working on a specific analysis in which we need to decompose the long M…
nttvy updated
3 weeks ago
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NOTE: if this is not a bug report, please use the [GitHub Discussions](https://github.com/facebookresearch/esm/discussions) for support questions (How do I do X?), feature requests, ideas, showcasing …
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Hello,
In the ECNet paper, the possibility to generate higher-order mutant from training on low-order varaints data is demonstrated.
However, the `MTH3_HAEAESTABILIZED_Tawfik2015` example provided …
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When preprocessing primary structure sequences (i.e. list of residue name strings), it has been shown that representing proteins in higher dimensional embedding space increases model performance capab…
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Contact: Hiplot Team / admin@hiplot.org
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dear author:
I have some questions about this method.
1)I cannot open the link you provided to download the model, but it was available a few weeks ago;
2)when I use the model to predict mutant …
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We have built a mutant library for cucumber and have completed resequencing some of the individual plants, finding a number of proteins with non-synonymous mutations. We have translated these proteins…
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**Bug description**
**Reproduction steps**
```python
import esm
model, alphabet = esm.pretrained.esm_msa1b_t12_100M_UR50S()
batch_converter = alphabet.get_batch_converter()
batch_size=5
p…